When to See Your Doctor

You should visit your doctor monthly to check how you are doing on this medication. If you get any of the following symptoms while you are taking Clarus, you must tell your doctor immediately because it may be necessary to stop Clarus:

• You get pregnant, or get pregnant within one month after stopping Clarus
• Changes in your mood such as becoming depressed, feeling sad, or having crying spells, and/or other signs of mental health problems such as:
  • Losing interest in your usual activities
  • Changes in your normal sleep patterns
  • Becoming more irritable or aggressive than usual (for example, temper outbursts, thoughts of violence)
  • Losing your appetite
  • Becoming unusually tired
  • Having trouble concentrating
  • Withdrawing from family and friends
  • Having thoughts about taking your own life (suicidal thoughts)
• Bad headaches, blurred vision, dizziness, nausea, vomiting, seizures (convulsions) and stroke
• Severe stomach pain, diarrhea, rectal bleeding
• Yellowing of the skin or eyes and/or dark urine
• Changes in your hearing or ringing in your ears
• Changes in your vision, especially at night; decreased night vision may occur and be sudden in some patients; take caution when driving at night 
• Persistent feelings of dry eyes
• Aches or pains in bones or joints, back pain, or difficulty in moving, muscle pain, especially after vigorous exercise. Muscle weakness with or without pain can be a sign of serious muscle damage. Tell a healthcare provider you are taking Clarus if you break a bone.
• Hives, swollen face or mouth, trouble breathing, fever, rash, red patches, bruises
• Fainting, become very thirsty, urinating a lot, feeling weak
• Chest pain, palpitations, vascular thrombotic disease, stroke, leg swelling, seizures (convulsions), slurred speech, problems moving or any other serious unusual problems
• Blisters, peeling skin, severe red/purple rash, fever, conjunctivitis (red or inflamed eyes)
• Multiple lesions and sores, particularly in your mouth, nose, eyes and genitals
• Your acne becomes worse.

Protect yourself from the sun

Clarus may increase your sensitivity to the sun. Avoid long periods in the sun. When you are in the sun, use a broad-spectrum sunscreen with an SPF of 30 or higher to help protect your skin. When choosing a sunscreen to use on your face, back and chest, choose one that’s oil-free, won’t cause blackheads (non-comedogenic), and won’t cause acne (non-acnegenic).